eISF & eTMF Sync
What happens at the site instantly reflects at the sponsor level. Total visibility, zero email attachments.
One source of truth for all your trial documents
Stop juggling spreadsheets and shared drives. Clincove's unified eISF and eTMF system ensures every document created at the site is instantly available to sponsors, monitors, and auditors — without a single email attachment.
From upload to audit-ready in seconds
Three steps replace weeks of manual document management
Upload or scan
Drag and drop documents, scan directly from paper, or forward emails. AI automatically classifies and routes each file to the correct TMF zone.
Sync instantly
Documents appear in both the site eISF and sponsor eTMF simultaneously. Version control, audit trails, and metadata are maintained automatically.
Stay audit-ready
Automated completeness checks flag missing documents. When inspectors arrive, generate a read-only inspector view in minutes — not weeks.
Built for modern document management
Everything you need to stay compliant and organized
Real-time Synchronization
When a site uploads a file to their eISF, it appears instantly in the sponsor's eTMF. Complete audit trail maintained automatically.
- Instant document availability
- Automatic version control
- Change tracking with full history
Audit-Ready Compliance
Every document is automatically tagged, indexed, and stored according to TMF Reference Model standards.
- TMF Reference Model compliance
- Automated indexing & metadata
- Inspector view access controls
Smart Classification
AI-powered document classification automatically sorts uploads into the correct TMF zones and sections. OCR extracts text for instant searchability.
- AI-powered document sorting
- OCR text extraction
- Full-text search across all files
21 CFR Part 11 eSignatures
Built-in compliant electronic signatures with identity verification. Full compliance with FDA regulations out of the box.
- FDA 21 CFR Part 11 compliant
- Identity verification
- Complete signature audit trail
Email-to-ISF Ingestion
Forward sponsor emails directly into the eBinder. Attachments are auto-extracted, classified, and filed — no manual downloads.
- Auto-extract attachments
- Smart sender recognition
- Chain-of-custody preserved
Built-in PDF Viewer
View, annotate, and approve documents without leaving the platform. Search within PDFs, rotate, zoom, and compare versions side by side.
- In-app document viewing
- Annotation and markup tools
- Side-by-side version comparison
Ready to eliminate document chaos?
Join hundreds of sites and sponsors who have unified their eISF and eTMF with Clincove.